UB303: Praja1

$479.59

In stock

SKU: UB-0303-0025 Category: Tag:

Specifications

Praja1 (along with Praja2, 53% identity) is a RING-H2 domain E3 (ubiquitin protein ligase) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E2 enzymes. Substrates for Praja1 include Dlxin-1 (MAGE-D1, human), which regulates Dlx5 dependent transcriptional function (involved in osteoblast differentiation), and ELF and Smad3, which are involved in the TGF-β signaling pathway implicated in gastrointestinal cancers.

Info

Species Human
Source E. coli
Tag His6-SUMO
Molecular Weight 71 kDa
Quantity 25 µg
Concentration Variable
Formulation
Storage -80°C, avoid freeze/thaw cycles

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