Publications March 8, 2023 Drug Discovery with UbiTest Technology UbiTest: Detection of polyubiquitinated proteins using TUBE based screening platforms by Gauthami S. Jalagadugula The… Matthew Krause 0 Love1
Publications December 14, 2022 Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation Hijacking the natural mechanism of the Ubiquitin Proteasome System (UPS) is emerging as a powerful… Isabelle Wentzel 0 Love1
Publications December 1, 2022 Discovering Unique Ubiquitin E3 Ligase Ligands to Unlock Targeted Protein Degradation Discovering Unique Ubiquitin E3 Ligase Ligands to Unlock Targeted Protein degradation Gauthami Jalagadugula, Alexandra Russell1+,… Isabelle Wentzel 0 Love1
Publications December 1, 2022 PROTACs and Molecular Glues: High-Throughput Quantitative Assays for Rationale Design PROTACs and Molecular Glues: High-Throughput Quantitative Assays for Rationale Design Authors: Janelle Pedroza1, Kenneth Wallace1,… Isabelle Wentzel 0 Love1
Publications November 4, 2019 Novel Approaches to PROTAC® Drug Discovery INTRODUCTION Proteolysis Targeting Chimeras (PROTACs) represent a promising set of drugs that target proteins without… Bryant Darnay 0 Love8
Publications November 8, 2018 Proteomics Discovery of Ubiquitylated Biomarkers for Neurodegenerative Disease ABSTRACT Ubiquitin-Proteasome system (UPS), along with chaperone mediated-autophagy (CMA) and macroautophagy, constitutes the protein… admin 0 Love7
Publications November 6, 2018 PROTAC Method of Action Presentation SEE THE LIFESENSORS PRESENTATION ON NOVEL PROTAC ASSAYS HERE. PLEASE CONTACT US FOR MORE INFORMATION ON… admin 0 Love5
Publications July 10, 2018 New Developments in Ubiquitomics: Discovery of poly-ubiquitylated proteins by novel chain-selective TUBEs LifeSensors Scientists Apurva Chaturvedi, Peter Foote, Li Liang, Dominic Vasturia, and Rajesh Singh recently presented… admin 0 Love5
Publications April 25, 2018 Deciphering the Ubiquitin Code with Poly-Ubiquitin Chain Selective Affinity Matrices LifeSensors recently presented the work of Rajesh Singh, Cari Sagum, Jianji Chen, Apurva Chaturvedi, Peter… admin 0 Love5
Publications April 19, 2018 Establishing Ubiquitylation Patterns in Cells: Efficient Monitoring of Oncogenic Ubiquitylation Activity Lifesensors recently presented the work of Peter Foote, Xialong Lu, Apurva Chaturvedi, and Rajesh Singh… admin 0 Love4