LifeSensors understands that early drug discovery programs are both labor intensive and time consuming. Besides involvement in both cellular and biochemical assays, biophysical characterization of potential hits is also a vital part of the drug discovery process – from early hit finding to mechanistic profiling during lead optimization. As part of our ongoing efforts to provide customers with services to further their drug discovery processes, LifeSensors introduces our Biophysical Assay Services.
Thermal Shift Assay
LifeSensors’ thermal shift assay is a quick and easy method to generate ligand-protein binding data and is widely employed across several target proteins and compounds including natural products.
Surface Plasmon Resonance
Generating experimental data for ligand binding to target proteins of interest as well as determination of ligand binding affinity (Kd) is essential for drug discovery. LifeSensors’ Surface Plasmon Resonance is a label-free optical technique that measures interactions in real time.