SUMO-Tag Protein Expression & Purification


Our SUMO-tag expression systems maximize the yield of soluble, functional proteins in E. coli, yeast, insect and mammalian cells. In this system, SUMO functions as both a chaperonin and an initiator of protein folding to dramatically improve the solubility and level of expression of your protein of interest. Our de-sumoylases efficiently and precisely remove SUMO tags, releasing your protein with the desired N-terminal amino acid. SUMO tags and de-sumoylases both have 6xHis-tags, making their subsequent removal fast and easy.

LifeSensors’ custom protein expression service is supported by our powerful SUMO expression platforms and our team of expert protein scientists. After a rapid development process, you will be provided with your desired quantity of active, highly pure protein.

You can choose the protein production, purification, or enzymatic activity determination service, among the many we offer, that that best suits your needs. We will provide you with a competitive quote for the purity you require. LifeSensors’ scientists use our proprietary SUMO expression technologies to enhance expression of your protein in prokaryotic, yeast, insect, or mammalian expression systems.



  • Enhanced protein expression with our proprietary SUMO systems optimized individually for prokaryotic, yeast, insect, and mammalian hosts
  • Increased solubility of the target protein
  • Efficient tag removal generating high yields of untagged protein of interest with the desired N-terminal amino acid
  • Simple purification methods


A presentation of our SUMO Protein Expression Platform is here.


Click here to see examples of our SUMO technology