Specifications
Tenovin 1 inhibits the deacetylase activity of SirT1 and SirT2. One of the substrates for SirT1 is p53 which is stabilized by acetylation of Lys-382. The ability of p53 to bind DNA is also enhanced by acetylation of Lys-382. Hence, inhibition of SirT1 by tenovin 1 leads to increased stability and activity of p53.
Info
| Purity | 99%; NMR consistent with structure |
| Quantity | 10 mg |
| Molecular Weight | 369.48 Da |
| Physical State | Powder |
| Solubility | 200mM in DMSO |
| CAS No. | 380315-80-0 |
| Storage | 4°C, (-20°C Long term). The product can be shipped at room temperature. |
Reviews
There are no reviews yet.