Specifications
A potent inhibitor of histone H2A ubiquitylation. Inhibits RNF2 and Ring1A, both of which are found in polycomb repressive complex 1 (PRC1). Does not inhibit RNF8 or RNF168. Inhibits accumulation of ubiquitin around DNA double-strand breaks (DSBs) as well as the repair of DSBs.
Info
| Purity | > 98% (TLC); NMR (conforms) |
| Quantity | 10 mg |
| Molecular Weight | 235.2 Da |
| Physical State | Dry yellow powder |
| Solubility | DMSO (25mg/mL) |
| CAS No. | 31083-55-3 |
| Storage | 4°C, (-20°C Long term). Store solutions at -20°C. The product can be shipped at room temperature. |
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