Alvespimycin hydrochloride (17-DMAG HCl) is a cell permeable potent HSP90 inhibitor with IC50 of 62 nM in a cell-free assay. 17-DMAG HCl is a geldanamycin analog that displays superior pharmacological properties and induces apoptosis in a variety of tumor cell lines. 17-DMAG HCl also inhibits angiogenesis.
|Purity||>98% by TLC|
|Quantity||1 mg, 5 mg|
|Molecular Weight||653.2 g/mol|
|Physical State||Lyophilized purple powder|
|Solubility||30 mg/ml in DMSO; 10 mg/mL in ethanol|
|Storage||-20°C, avoid freeze/thaw cycles|