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SI9880: SMER3

LifeSensors SI9880 (SMER3) is a specific inhibitor of the ubiquitin E3 ligase SCFMET30, used in research to modulate protein degradation and ubiquitin pathways.

$250.00$1,246.00

Applications

  • Cell-based or in vitro inhibition of SCFMET30
Small Molecule Enhancer of Rapamycin 3 (SMER3) is a specific inhibitor of the ubiquitin E3 ligase SCFMET30. SMER3 binds directly to the F-box subunit Met30 and blocks binding to the SCF core complex. This inhibitor is cell permeable. Significant inhibition is typically seen at 30-100 μM.

Info

Purity >98% (TLC), NMR (conforms)
Quantity 10 mg, 25 mg, 50 mg
Molecular Weight 224.2 Da
Physical State Yellow powder
Solubility DMSO (20mg/ml), requires heating
CAS No. 67200-34-4
Storage 4°C, (-20°C Long term). Store solutions at -20 °C for up to 2 months. The product can be shipped at room temperature.

Applications

  • Cell-based or in vitro inhibition of SCFMET30

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