SI9880: SMER3

Small Molecule Enhancer of Rapamycin 3 (SMER3) is a specific inhibitor of the ubiquitin E3 ligase SCFMET30. SMER3 binds directly to the F-box subunit Met30 and blocks binding to the SCF core complex. This inhibitor is cell permeable. Significant inhibition is typically seen at 30-100 μM.

Info

Purity	>98% (TLC), NMR (conforms)
Quantity	10 mg, 25 mg, 50 mg
Molecular Weight	224.2 Da
Physical State	Yellow powder
Solubility	DMSO (20mg/ml), requires heating
CAS No.	67200-34-4
Storage	4°C, (-20°C Long term). Store solutions at -20 °C for up to 2 months. The product can be shipped at room temperature.