A cell-permeable, non-peptide inhibitor of MDM2-p53 interactions (Ki=120nM). Treatment of cancer cells activates p53 and accumulation of p21, p53, and MDM2. The structure mimics three p53 residues involved in binding to MDM2.
|Purity||>97% (TLC, HPLC), NMR (conforms)|
|Molecular Weight||340.4 Da|
|Physical State||White solid|
|Storage||4°C, (-20°C Long term). The product can be shipped at room temperature.|