AC1005: LY-294002


SKU: AC-1005 Categories: ,


LY-294002 is a cell permeable highly selective inhibitor of phosphatidylinositol 3-kinase (IC50 = 0.31, 0.73, 1.06 and 6.60 µM for PI 3-Kβ, PI 3-Kα, PI 3-Kδ and PI 3-Kγ respectively). It inhibits autophagy in rat hepatocytes (IC50 = 10 µM). LY-294002 is an extremely useful tool for determining the role of PI 3-K in cellular signaling.  It is more stable in solution than Wortmannin, and also blocks autophagosome formation.


Purity >98% by TLC
Quantity 5 mg, 25 mg
Molecular Weight 307.4 g/mol
Physical State Lyophilized white powder
Solubility 20mg/mL in warm DMSO; 8 mg/mL in warm ethanol
CAS No. 154447-36-6
Storage -20°C, avoid freeze/thaw cycles

Additional information


5 mg, 25 mg


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