AC1003: Chloroquine diphosphate

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SKU: AC-1003 Categories: ,

Specifications

Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. It inhibits autophagy in a variety of cell lines, induces cell death in breast cancer cell lines, and displays antitumor and antimetastatic activity in mouse models of breast cancer. Chloroquine diphosphate eliminates cancer stem cells via deregulation of Jak2 and DNMT1. It displays synergy when combined with the Raf inhibitor, vemurafenib, in brain tumors. It is also cell permeable and active in vivo.

Info

Purity >98.0% by TLC
Quantity  5mg, 25mg, 50mg
Molecular Weight 515.9 g/mol
Physical State Lyophilized white powder
Solubility 25 mg/mL in water
CAS No. 50-63-5
Storage solutions at -20°C, avoid freeze/thaw cycles; desiccated at ambient temperature

Additional information

Weight

5 mg, 25 mg, 50 mg

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