Specifications
Based on UBA domains known to possess a high affinity for ubiquitin, Tandem Ubiquitin Binding Entities (TUBEs) have been developed for the isolation and identification of ubiquitinated proteins. TUBEs display up to a 1000-fold increase in affinity for polyubiquitin moieties over the single ubiquitin binding associated domain (UBA). In addition, TUBEs have been demonstrated to protect polyubiquitinated proteins from both deubiquitination and proteasome-mediated degradation, allowing for the detection of relatively low abundant proteins that cannot be detected with current technologies.
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Info
| Tag | GST |
| Molecular Weight | 56 kDa |
| Physical State | Liquid |
| Quantity | 200 µg and 1 mg |
| Concentration | Variable |
| Storage | -80°C, avoid freeze/thaw cycles |
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