UB230: UBE2Z

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Specifications

UBE2Z is a ubiquitin conjugating enzyme (E2) that appears to be a specific substrate for the Uba6 ubiquitin activating enzyme (E1). Little is known about the specific function of this E2, but it has been implicated as a proapoptotic enzyme. The protein has been cited to exist as alternate splice variants, a 354 amino acid form and a 181 amino acid form (isoform 2). LifeSensors currently offers the second isoform.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 28,075.4 Da
Quantity 0.8 nmol, 3.0 nmol
Concentration 40 µM
Formulation 25 mM Tris pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Additional information

Nanomole

0.8 nmol, 3 nmol

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Applications

  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes

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