UBE2T can mediate the transfer of ubiquitin from ubiquitin-activating enzyme E1 to a substrate protein or E3 ligase. This E2 enzyme has been shown to be essential for the Fanconi anemia pathway. UBE2T conjugating activity is involved with the monoubiquitylation of FANCD2, co-functioning with the E3 ligase FANCL.
|Molecular Weight||34,540.3 Da|
|Quantity||0.8 nmol, 3.0 nmol|
|Formulation||25 mM Tris pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol|
|Storage||-80°C, avoid freeze/thaw cycles|