Specifications
UBE2E2 is an E2 conjugation enzyme that is involved in the ubiquitylation of target substrates, along with E1 and E3 enzymes. It is a protein that in humans is encoded by the UBE2E2gene. Amino acid sequence within the UBC domain of UBE2E2 shares over 90% identity with human UbcH6, mouse UbcM2, and Drosophila UbcD2, whereas the N-terminal region shows little amino acid sequence similarity with known proteins. UBE2E2 forms a thioester bond with ubiquitin in an E1-dependent manner and mediates the transfer of ubiquitin from a ubiquitin-activating enzyme (E1) to a substrate protein or E3 ligase.
Info
| Species | Human |
| Source | E. coli |
| Tag | None |
| Molecular Weight | 22,255.3 Da |
| Quantity | 0.8 nmol, 3.0 nmol |
| Concentration | 40 µM |
| Formulation | 20 mM Tris, pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol |
| Storage | -80°C, avoid freeze/thaw cycles |
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