UB227: UBE2G2

LifeSensors UB227 is a human UBE2G2 enzyme involved in endoplasmic reticulum-associated degradation (ERAD), essential for studying protein ubiquitination and degradation pathways.

$196.00 – $390.00

SKU UB-0227 Categories E2 Ubiquitin Conjugating Enzymes, Ubiquitin Ligases and Enzymes

Product Advantages

Applications

Identify cognate E2/E3 pairs
Characterize upregulation/downregulation of E2 enzymes
Build poly-ubiquitin chains
Characterize ubiquitin chain specificity of E2 enzymes
Analyze expression of E2 enzymes

Benefits

Untagged (native) E2 conjugation enzyme

UBE2G2 is the human homolog of yeast Ubc7, and has been demonstrated to be involved in endoplasmic reticulum associated degradation (ERAD). Structural studies indicate that this single domain protein possesses a loop region, likely involved in interaction(s) with the RING domain that impart binding specificity and/or stability. This 165 amino acid protein is ubiquitously expressed, highly in muscle tissues.

Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	18,565.3 Da
Quantity	0.8 nmol, 3.0 nmol
Concentration	40 µM
Formulation	50 mM Tris pH 7.5, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage	-80°C, avoid freeze/thaw cycles