UB208H: UBE2R1 (CDC34), His6

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Specifications

236 amino acid product of the CDC34 gene. It controls cellular proliferation through regulation of p27/Kip1 protein levels. Blocking CDC34 activity enhances the anti-myeloma effects of Bortezomib.

Info

Species Human
Source E. coli
Tag His6
Molecular Weight 27,730.4 Da
Quantity 0.8 nmol, 3.0 nmol
Concentration 40 µM
Formulation 50 mM Tris pH 7.5, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Additional information

Nanomole

0.8 nmol, 3 nmol

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  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes

Benefits

  • Untagged (native) E2 conjugation enzyme