UB209: UBE2R2 (Ubc3B)




UBE2R2 is similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. UBE2R2 is a 238 amino acid (27.2 kD) pre-protein from chromosome 9. After CK2-mediated UBE2R2 phoshorylation, it binds to the F-Box protein beta-TrCP, which is the subunit recognition subunit of an SCF E3 ligase. UBE2R2 may be involved in degradation of beta-catenin.


Species Human
Source E. coli
Tag None
Molecular Weight 27,166.1 Da
Quantity 0.8 nmol, 3.0 nmol
Concentration 40 µM
Formulation TBS
Storage -80°C, avoid freeze/thaw cycles

Additional information


0.8 nmol, 3 nmol


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  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes


  • Untagged (native) E2 conjugation enzyme