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Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9619: PR-619

LifeSensors’ SI9619 (PR-619) is a cell-permeable, reversible, non-selective inhibitor of deubiquitinases and ubiquitin-like isopeptidases, inducing ubiquitin and SUMO protein accumulation with IC50 of 5-20 µM for cell biology and drug discovery research

Price range: $100.00 through $398.00

PR-619 is a non-selective, reversible inhibitor of deubiquitinases/deubiquitylases (DUBs) and ubiquitin-like isopeptidases. PR-619 inhibits many deubiquitinating enzymes in the 5-20 µM range. Additionally, PR-619 is cell-permeable and treatment of cells results in the accumulation of both ubiquitin and sumo-conjugated proteins.

Info

Purity ≥ 95% (RP-HPLC)
Quantity 5mg; 25mg
Molecular Weight 223.28 gm/mol; measured M+H+ = 224.11
Physical State Dry powder
Solubility > 5 mg/mL in DMSO
CAS No.
Storage 4 °C, with long term storage down to -20°C. Product can be shipped at room temperature.
This product has been cited 1 time.
  • Non-specific inhibition of isopeptidases
  • Cell biology
  • Preparation of cell/tissue lysates
  • Drug discovery
  • Benefits: cell-permeable

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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