Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI9619: PR-619

LifeSensors’ SI9619 (PR-619) is a cell-permeable, reversible, non-selective inhibitor of deubiquitinases and ubiquitin-like isopeptidases, inducing ubiquitin and SUMO protein accumulation with IC50 of 5-20 µM for cell biology and drug discovery research

Price range: $100.00 through $483.00

PR-619 is a non-selective, reversible inhibitor of deubiquitinases/deubiquitylases (DUBs) and ubiquitin-like isopeptidases. PR-619 inhibits many deubiquitinating enzymes in the 5-20 µM range. Additionally, PR-619 is cell-permeable and treatment of cells results in the accumulation of both ubiquitin and sumo-conjugated proteins.

Info

Purity ≥ 95% (RP-HPLC)
Quantity 5mg; 25mg
Molecular Weight 223.28 gm/mol; measured M+H+ = 224.11
Physical State Dry powder
Solubility > 5 mg/mL in DMSO
CAS No.
Storage 4 °C, with long term storage down to -20°C. Product can be shipped at room temperature.
This product has been cited 1 time.
  • Non-specific inhibition of isopeptidases
  • Cell biology
  • Preparation of cell/tissue lysates
  • Drug discovery
  • Benefits: cell-permeable

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
We typically respond within 24 hours

Visit Anytime

271 Great Valley Parkway Malvern, PA 19355

Send us a Message

Have a question about our solutions? We’d love to hear from you.
* Required fields

More from This Category

LifeSensors SI9669 is a specialized ubiquitin reagent designed for advanced research in protein regulation and ubiquitination pathways, supporting precise biochemical....
LifeSensors SI9644 is a potent, selective inhibitor of USP7 deubiquitinase, used in research to study protein regulation and cancer therapy....
LifeSensors SI9634 is a specialized ubiquitin reagent designed for advanced protein research, enabling precise studies of ubiquitin signaling and protein....
LifeSensors UE903 UbiQuant™ S Plate enables high-throughput, quantitative measurement of ubiquitination levels in cell lysates, supporting efficient PROTAC screening and....

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Menu

Learning Center