Specifications
PR-619 is a non-selective, reversible inhibitor of deubiquitinases/deubiquitylases (DUBs) and ubiquitin-like isopeptidases. PR-619 inhibits many deubiquitinating enzymes in the 5-20 µM range. Additionally, PR-619 is cell-permeable and treatment of cells results in the accumulation of both ubiquitin and sumo-conjugated proteins.
Info
Purity | ≥ 95% (RP-HPLC) |
Quantity | 5 mg; 25 mg |
Molecular Weight | 223.28 Da; measured M+H+ = 224.11 |
Physical State | Dry powder |
Solubility | > 5 mg/mL in DMSO |
CAS No. | |
Storage | 4 °C, with long term storage down to -20°C. Product can be shipped at room temperature. |
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