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  • Our Technologies
    • PROTAC & DUBTAC Drug Discovery
    • Tandem Ubiquitin Binding Entities (TUBEs)
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    • SUMO Technology and Difficult to Express Proteins
      • Polypeptide Manufacturing
      • Therapeutic Proteins, Dramatic Enhancement
      • Nanobodies and Single Chain Antibodies
      • Vaccine Manufacturing with SUMO
      • Gene Therapy: SUMO to the Rescue
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    • PROTACs & Molecular Glues
      • PROTAC® Degradation Assays
      • PROTAC® Ubiquitination Assays
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      • PROTAC Ternary Complex Assays
      • PROTAC for Cancer
      • PROTAC for Neuroscience
    • E3 Ubiquitin Ligases Profiling & Screening
      • Thermal Shift Assay for E3 Ligases
      • Surface Plasmon Resonance for E3 Ligases
      • Biochemical Assays (High Throughput Screening)
      • E3 TR-FRET Assay
      • E3 ELISA Assay
      • Cellular Assays (Hit Validation)
      • UbiQuant ELISA (Cellular)
      • UbiTest Substrate Validation
    • DUB Assays, Screening & Profiling
      • Ubiquitin Fluorophore Assay (Rhodamine, AMC, VME)
      • Physiological DUB Assays
      • Di-Ubiquitin IQF Assay (Patented)
      • CHOP Assay-  Ubiquitin, SUMO, ISG15 & NEDD8 (Patented)
    • SUMO-Tag Protein Expression & Purification
      • SUMOpro
      • Bacterial 
      • Mammalian
      • SUMOstar 
      • Advanced Therapeutic Applications
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      • Autophagy Modulators
      • UPP Inhibitor Library
      • E1-E2-E3 Inhibitors
      • DUB inhibitors
      • Proteasome Inhibitors
      • p97 Inhibitors
    • TUBEs: Ubiquitin Affinity Matrix
      • Pan-Selective TUBEs
      • K48 TUBEs HF
      • K63 TUBEs
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      • TUBEs for Detection
      • Magnetic TUBEs
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    • SUMO Protein Expression System
      • Bacteria
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Sep 21
Love0

LifeSensors is invited to speak at Discovery on Target 2023 – Breakthrough Molecules with Unique Molecular Glue & PROTAC Platform

By Isabelle Wentzel News, Press Releases No Comments

MALVERN, Pa., SEP 21, 2023 — LifeSensors Inc., a Biotech and Drug Discovery Company focused on PROTAC, molecular glue drug discovery and neurodegeneration diagnostics has been invited to speak at the…

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May 30
Love2

LifeSensors is Partnering at BIO International Convention 2023

By Isabelle Wentzel News, Press Releases No Comments

MALVERN, PA., May 30, 2023 — LifeSensors Inc., a Biotech and Drug Discovery Company focused on PROTACs, molecular glues, and neurodegeneration diagnostics will disclose direct methods to detect PROTAC & molecular glue…

Read More
Mar 08
Love0

Tragedy to Transformation – Molecular Glue Sparks the Field of Targeted Protein Degradation

By Isabelle Wentzel Blog, Education No Comments

By: Isabelle Wentzel   Devastating Origins In the late 1950s and early 1960s, pregnant women who experienced nausea and morning sickness were prescribed thalidomide, a sedative drug meant to treat…

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Mar 08
Love0

Drug Discovery with UbiTest Technology

By Matthew Krause Publications No Comments

UbiTest: Detection of polyubiquitinated proteins using TUBE based screening platforms by Gauthami S. Jalagadugula The ubiquitin proteasome system (UPS) is a highly regulated mechanism that controls many cellular processes through…

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Dec 14
Love0

Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation

By Isabelle Wentzel Publications No Comments

Hijacking the natural mechanism of the Ubiquitin Proteasome System (UPS) is emerging as a powerful medium in drug discovery through which Dr. Kadimisetty uses “TUBEs” as ubiquitin-binding entities to monitor…

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Dec 01
Love0

Discovering Unique Ubiquitin E3 Ligase Ligands to Unlock Targeted Protein Degradation

By Isabelle Wentzel Publications No Comments

Discovering Unique Ubiquitin E3 Ligase Ligands to Unlock Targeted Protein degradation Gauthami Jalagadugula, Alexandra Russell1+, Kenneth Wallace1+, Janelle Pedroza and Abdul Haseeb1 * Introduction PROteolytic TArgeting Chimeras (PROTACs) have emerged…

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Dec 01
Love0

PROTACs and Molecular Glues: High-Throughput Quantitative Assays for Rationale Design

By Isabelle Wentzel Publications No Comments

PROTACs and Molecular Glues: High-Throughput Quantitative Assays for Rationale Design Authors: Janelle Pedroza1, Kenneth Wallace1, Derrick Padykula, Alexandra Russell1, and Karteek Kadimisetty*1 Introduction PROTACs have emerged as new class of…

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Sep 08
Love0

Profiling E3 ligase compounds and the Implications in Drug Discovery

By Matthew Krause Blog, Education No Comments
By: Abdul Haseeb, Ph.D.   Drugging the Undruggable Tremendous progress in genomics, transcriptomics and proteomics has led to the discovery of thousands of new drivers of disease, but drug discovery...
Read More
Sep 01
Love2

Accelerating PROTAC drug discovery: Establishing a Relationship Between Ubiquitination and Target Protein Degradation

By Matthew Krause Education, Press Releases No Comments

MALVERN, Pa., SEP 1, 2022 – LifeSensors Inc., a Biotech and Drug Discovery Company focused on PROTAC, molecular glues, and neurodegeneration diagnostics, is pleased to announce that Lifesensors has published…

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Aug 30
Love6

LifeSensors is Attending ASCB | EMBO Cell Bio 2022

By Matthew Krause News, Press Releases No Comments
LifeSensors is Attending ASCB | EMBO Cell Bio 2022 MALVERN, PA., AUG 30, 2022 -- LifeSensors Inc., a Biotech and Drug Discovery Company focused on PROTACs, molecular glues, and neurodegeneration...
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PROTAC IS A REGISTERED TRADEMARK OF ARVINAS OPERATIONS, INC., AND IS USED UNDER LICENSE.

LIFESENSORS

Our business development team works with customers to develop simple and cost effective work plans. We facilitate a smooth transfer of our technology, offering transfer and licensing terms that fit the needs of the client’s laboratory and organization. Our team is dedicated to providing state-of-the-art products to help put your research and development efforts into the forefront. We’ve developed non-traditional approaches and scalable discounts to bring our technology to your lab.

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CONTACT US

271 Great Valley Parkway
Malvern, PA 19355

 
 
Phone: 610.644.8845
Fax: 610.644.8616

LifeSensors Inc.

    Menu
    • Home
    • Our Technologies
      • PROTAC & DUBTAC Drug Discovery
      • Tandem Ubiquitin Binding Entities (TUBEs)
      • Ubiquitin and Ubiquitin Chains
      • SUMO Technology and Difficult to Express Proteins
        • Polypeptide Manufacturing
        • Therapeutic Proteins, Dramatic Enhancement
        • Nanobodies and Single Chain Antibodies
        • Vaccine Manufacturing with SUMO
        • Gene Therapy: SUMO to the Rescue
      • Molecular Glue Degraders
      • Neurodegeneration
    • R&D Services
      • PROTACs & Molecular Glues
        • PROTAC® Degradation Assays
        • PROTAC® Ubiquitination Assays
        • Target Exploration and Validation
        • Novel E3 Ligases for PROTAC ®
        • PROTAC Ternary Complex Assays
        • PROTAC for Cancer
        • PROTAC for Neuroscience
      • E3 Ubiquitin Ligases Profiling & Screening
        • Thermal Shift Assay for E3 Ligases
        • Surface Plasmon Resonance for E3 Ligases
        • Biochemical Assays (High Throughput Screening)
        • E3 TR-FRET Assay
        • E3 ELISA Assay
        • Cellular Assays (Hit Validation)
        • UbiQuant ELISA (Cellular)
        • UbiTest Substrate Validation
      • DUB Assays, Screening & Profiling
        • Ubiquitin Fluorophore Assay (Rhodamine, AMC, VME)
        • Physiological DUB Assays
        • Di-Ubiquitin IQF Assay (Patented)
        • CHOP Assay-  Ubiquitin, SUMO, ISG15 & NEDD8 (Patented)
      • SUMO-Tag Protein Expression & Purification
        • SUMOpro
        • Bacterial 
        • Mammalian
        • SUMOstar 
        • Advanced Therapeutic Applications
        • Mammalian
      • Mass Spectrometry Proteomics
        • TUBE-Based Mass Spectrometry
        • E3 Ligase Substrate ID
        • DUB Substrate ID
        • Whole Cell Proteomics
        • Target Substrate Lysine Ubiquitination ID
        • Ubiquitin Chain Diversity ID
      • Ligand Binding Assays
        • Thermal Shift Assays 
        • Surface Plasmon Resonance
        • Fluorescence Polarization
    • Products
      • PROTAC Tools
        • PROTAC Ubiquitin Assays
        • PROTAC Ubiquitin Plates
        • In Vitro Assay in PROTAC
        • Small Molecule Modulators and PROTACs
        • Autophagy Modulators
        • UPP Inhibitor Library
        • E1-E2-E3 Inhibitors
        • DUB inhibitors
        • Proteasome Inhibitors
        • p97 Inhibitors
      • TUBEs: Ubiquitin Affinity Matrix
        • Pan-Selective TUBEs
        • K48 TUBEs HF
        • K63 TUBEs
        • Linear- M1 TUBE1
        • TUBEs for Detection
        • Magnetic TUBEs
        • Antibodies
        • Ubiquitin Antibodies
        • DUB and Ubiquitin Like Isopeptidase Antibodies
        • SUMO Antibodies
      • Ubiquitin Ligases and Enzymes
        • E1 Ubiquitin Activating Enzymes
        • E2 Ubiquitin Conjugating Enzymes
        • E3 Ubiquitin Ligases
        • Proteasomal Research Tools
        • Kits and Plates
        • E1-E2-E3 Assays
        • High-throughput Plates
        • UbiTest
        • UbiQuant
      • Deubiquitinating enzymes (DUBs)
        • USP Family of DUBs
        • UCH Family of DUBs
        • OTU Family of DUBs
        • JAMM Family of DUBs
        • MJD Family of DUBs
        • Viral and Bacterial DUBs
        • Deneddylases
        • DeSUMOylases
      • SUMO Protein Expression System
        • Bacteria
        • Mammalian cells
        • Insect cells
        • Yeast
        • SUMO Protease Enzymes
        • SUMO Protease 1
        • SUMO Protease 2
        • SUMOstar Protease
      • Ubiquitin Chains and Derivatives
        • Ubiquitin and Neuro-degeneration
        • Ubiquitin Chains
        • Ubiquitin K to R mutants
        • Ubiquitin Derivatives
        • Sumo Derivatives Chain
        • Isotopically-Labeled ubiquitin
        • CHOP2 Reporter Assays
        • IQF Diubiquitins
    • Resources
      • Discussion Forum
      • FAQs
      • PROTAC DRUG DISCOVERY
      • Mass Spec
      • SUMO
      • TUBES
    • Media
      • News
      • Press Releases
      • Publications
      • Blog Posts
    • About Us
      • About LifeSensors
      • Careers
      • Contact Us
    CLOSE

PROTAC

  • PROTAC Products

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    • PROTAC Compounds
    • Tools for PROTAC R&D
  • Tools for PROTAC Research and Development

    • TR-FRET in-vitro Ubiquitylation Assay
    • UbiTest
    • ELISA-based in-vitro Ubiquitylation Assay
    • UbiQuant S and AlphaLISA