AC1002: 3-Methyladenine

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SKU: AC-1002 Categories: ,

Specifications

3-Methyladenine inhibits autophagy by blocking autophagosome formation via inhibition of type III phosphatidylinositol 3-kinases (PI-3K). It protects 1321N1 astrocytoma cells against pyocyanin and hydroxyphenazine-induced toxicity. Inhibition of autophagy by 3-MA leads to enhanced apoptosis induced by a variety of agents including celastrol, cisplatin and sorafenib in several different cell lines.

Info

Purity >98% by TLC
Quantity 25 mg, 50 mg, 100 mg
Molecular Weight 149.2 g/mol
Physical State Lyophilized white powder
Solubility 3 mg/ml in DMSO; 10 mg/mL in warm DMF; 5 mg/mL in water
CAS No. 5142-23-4
Storage -20°C, avoid freeze/thaw cycles

Additional information

Weight

25 mg, 50 mg, 100 mg

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