AC1007: Vinblastine Sulfate

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SKU: AC-1007 Categories: ,

Specifications

Vinblastine sulfate is a semisynthetic alkaloidal anticancer agent. It induces cell cycle arrest at G2/M phase by inhibiting mitotic spindle formation. It also inhibits normal microtubule assembly and induces aberrant tubulin polymerization. Vinblastine sulfate induces apoptosis in a variety of cell lines, inhibits autophagosome maturation, and palmitoylation of tubulin. Vinblastine sulfate also suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay.

Info

Purity 98% by TLC
Quantity 5 mg, 25 mg
Molecular Weight 909.1 g/mol
Physical State Lyophilized white crystalline powder
Solubility 25 mg/mL in DMSO; 50 mg/mL in water
CAS No. 143-67-9
Storage -20°C, avoid freeze/thaw cycles

Additional information

Weight

5 mg, 25 mg

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Autophagy inhibitor: inhibits autophagosome maturation