UPS Inhibitor

SI9629: IU1

$195.00

In stock

SKU: SI-9629-0010 Categories: , Tag:

Specifications

IU1 is a cell-permeable, reversible, and selective inhibitor of the proteasome-associated DUB USP14 (IC50 < 4 µM). IU1 enhances proteasome activity and substrate proteolysis. IU1 promotes cell survival under stress conditions and selectively stimulates ubiquitin-dependent protein degradation in vitro.

Info

Purity > 98% (TLC), NMR (Conforms)
Quantity 10 mg
Molecular Weight 300.4 Da
Physical State Beige powder
Solubility DMSO (30 mg/mL)
CAS No. 314245-33-5
Storage 4°C, (-20°C Long term). The product can be shipped at room temperature.

Additional information

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Applications

  • Inhibition of USP14
  • Cell biology
  • Drug discovery
  • Benefits: cell-permeable

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