Specifications
IU1 is a cell-permeable, reversible, and selective inhibitor of the proteasome-associated DUB USP14 (IC50 < 4 µM). IU1 enhances proteasome activity and substrate proteolysis. IU1 promotes cell survival under stress conditions and selectively stimulates ubiquitin-dependent protein degradation in vitro.
Info
Purity | > 98% (TLC), NMR (Conforms) |
Quantity | 10 mg |
Molecular Weight | 300.4 Da |
Physical State | Beige powder |
Solubility | DMSO (30 mg/mL) |
CAS No. | 314245-33-5 |
Storage | 4°C, (-20°C Long term). The product can be shipped at room temperature. |
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