Specifications
Vinblastine sulfate is a semisynthetic alkaloidal anticancer agent. It induces cell cycle arrest at G2/M phase by inhibiting mitotic spindle formation. It also inhibits normal microtubule assembly and induces aberrant tubulin polymerization. Vinblastine sulfate induces apoptosis in a variety of cell lines, inhibits autophagosome maturation, and palmitoylation of tubulin. Vinblastine sulfate also suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay.
Info
Purity | 98% by TLC |
Quantity | 5 mg, 25 mg |
Molecular Weight | 909.1 g/mol |
Physical State | Lyophilized white crystalline powder |
Solubility | 25 mg/mL in DMSO; 50 mg/mL in water |
CAS No. | 143-67-9 |
Storage | -20°C, avoid freeze/thaw cycles |
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