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Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UB318: Untagged Parkin E3 Ligase

LifeSensors UB318 is untagged Parkin E3 ligase with >95% purity, essential for studying ubiquitination and neurodegeneration in Parkinson’s disease research.

$602.00

In stock

In stock

Encoded by the PARK2 gene, the E3 ligase Parkin is part of the multi-protein E3 complex that encodes substrate proteins for degradation in the Ubiquitin-Proteosome Pathway. The precise function of this protein is unknown; however, mutations in this gene are known to cause a familial form of Parkinson’s disease known as autosomal recessive juvenile Parkinson’s disease (AR-JP). Parkin is described to be necessary for mitophagy (autophagy of mitochondria).

Product Information

Purity: > 95% by SDS-PAGE
Molecular Weight: 51.6 Da
Physical State: Liquid, 50 mM Tris, pH 7.5, 0.15 M NaCl, 10% Glycerol
Quantity: 25 µg
Storage: -80o C.  Avoid repeated freeze/thaw cycles
  • For use in investigating and research of the Parkin and PINK1 pathway of mitophagy and/or drug discovery.

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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