SI9689: NSC-632839

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Specifications

A pan-specific ubiquitin & ubiquitin-like isopeptidase inhibitor. Inhibits USP2, USP7, and SENP2 with EC50 values of 45 ± 4 μM, 37 ± 1 μM, and 9.8 ± 1.8 μM, respectively. Does not affect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway. Cell permeable.

Info

Purity >98% (HPLC); NMR (Conforms)
Quantity 10 mg, 50 mg
Molecular Weight 339.9 Da
Physical State Yellow Powder
Solubility DMSO (8 mg/mL)
CAS No. 157654-67-6
Storage 4°C, (-20°C Long term). Store solutions at -20°C for up to 1 month.  The product can be shipped at room temperature.

Additional information

Weight

10 mg, 50 mg

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