Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SI6303P: K63-Linked Tri-Ubiquitin (Phosphorylated)

LifeSensors’ SI6303P is human K63-linked tri-ubiquitin, phosphorylated, produced in E. coli, ideal for studying ubiquitin signaling and protein regulation in research

$695.00

K63 chains traditionally play a role in intracellular signalling, trafficking, and autophagy. Phospho-ubiquitin chains represent a specialized class of polyubiquitin characterized by phosphorylation at Serine 65 and play a central role in mitophagy signaling pathways. K63 Tri-Ubiquitin (phosphorylated) is a trimeric chain of wild-type ubiquitin, wherein ubiquitin monomers are linked together via an isopeptide bond between Lysine 63 and the C-terminal Glycine. The chains are then enzymatically phosphorylated at the Ser65 position. Info
Species Human
Source E. coli
Tag None
Molecular Weight 25766-25926 Da (depending on degree of phosphorylation)
Quantity 25µg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl
Storage -80°C, avoid freeze/thaw cycles
  • Investigation of phospho-ubiquitin chain specificity and selectivity
  • Studies on the role of phospho-ubiquitin chains in protein degradation pathways (e.g., proteasomal and autophagic degradation)
  • Analysis of phospho-ubiquitin-mediated signaling pathways and cellular responses
  • Structural studies to elucidate the architecture and dynamics of phospho-ubiquitin chains

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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