SI1112: DUB-Resistant K11-Linked Di-Ubiquitin

$223.00

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This product is made-to-order; Please allow 2 weeks for delivery

DUB-resistant, K11-linked Di-ubiquitin (Ub2) contains an amino acid substitution near the C-terminus of the distal ubiquitin that renders it resistant to deubiquitylases (DUBs). DUB-resistant ubiquitin chains are ideal reagents for structural or binding studies with deubiquitylases or other ubiquitin binding proteins. They can also be used as inhibitors or to determine the linkage-specificity of DUBs. The product contains a wild-type C-terminus on the proximal ubiquitin.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 17,123.7 Da
Quantity 100 µg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 1 mM EDTA
Storage -80°C, avoid freeze/thaw cycles

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Application

Structural or binding studies with deubiquitylases and other ubiquitin binding proteins.  Inhibition or determination of linkage-specificity of DUBs

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