Specifications
Parkin is a crucial regulator of mitochondrial homeostasis and plays a pivotal role in mitophagy, the process of selectively removing damaged mitochondria. Phosphorylation of Parkin at serine 65 is a key post-translational modification that activates its E3 ubiquitin ligase activity and promotes mitochondrial clearance. This antibody enables researchers to investigate the dynamics of Parkin phosphorylation and its impact on mitophagy in various cellular and disease contexts. With its high specificity and sensitivity, the Phospho-Parkin (Ser65) antibody offers valuable insights into the mechanisms underlying mitochondrial quality control and may hold therapeutic implications in neurodegenerative diseases associated with mitochondrial dysfunction.
Info
| Species | Rabbit |
| Source | Affinity purified |
| Tag | None |
| Molecular Weight | 50 kDa |
| Quantity | 100µl |
| Concentration | Variable |
| Formulation | Phosphate-buffered saline with 50% glycerol |
| Storage | -20°C, avoid freeze/thaw cycles |
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