Generating experimental data for ligands binding to target proteins of interest as well as determination of ligand binding affinity (Kd) is essential for drug discovery. The thermal shift assay is a quick and easy method to generate ligand-protein binding data and is widely employed across several target proteins and compounds, including natural products.

LifeSensors has established a robust protein thermal shift assay platform and offer services to facilitate ligand discovery and characterization for clients. Together with our proprietary protein expression and purification technology, LifeSensors can help you discover ligands for difficult to express target proteins.