UB301: MuRF1

MuRF1 (Muscle-specific RING-finger protein 1) is an E3 (ubiquitin protein ligase) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E2 enzymes. MuRF1 is also known as TRIM63 (tripartite motif containing 63) containing a RING-finger/B-box/coiled-coil tripartite fold and is a member of the RING-domain E3 family. MuRF1 has been implicated as a component of atrophy-associated accelerated proteolysis. It is upregulated in a number of different models of atrophy and interacts with numerous myofibrillar proteins.

Info

Species	Human
Source	E. coli
Tag	His6-SUMO
Molecular Weight	40 kDa
Quantity	25 µg
Concentration	Variable
Formulation
Storage	-80°C, avoid freeze/thaw cycles