UB200 E2 Selection Panel

UB317A: Parkin (phosphorylated)

$385.00

In stock

SKU: UB-317A-0025 Categories: , Tag:

Specifications

Encoded by the PARK2 gene, the E3 ligase Parkin is part of the multi-protein E3 complex that encodes substrate proteins for degredation in the Ubiquitin-Proteosome Pathway. The precise function of this protein is unknown; however, mutations in this gene are known to cause a familial form of Parkinson’s disease known as autosomal recessive juvenile Parkinson’s disease (AR-JP). Parkin is described to be necessary for mitophagy (autophagy of mitochondria).

Info

Species Human
Source E. coli
Tag His6SUMO
Molecular Weight 64 kDa
Quantity 25 µg
Concentration Variable
Formulation
Storage -80°C, avoid freeze/thaw cycles

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