DB701-25µg SENP1core

DB505: USP14

$125.00

In stock

Specifications

USP14 (Ubiquitin Specific Protease 14) is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome-targeted ubiquitinated proteins. This enzyme serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded ER proteins via interaction with ERN1. It also plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.

Info

Species Human
Source E. coli
Tag His6 + SUMO
Molecular Weight 68 kDa
Quantity 25 µg
Concentration Variable
Formulation
Storage -80°C, avoid freeze/thaw cycles

Additional information

SKU

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Applications

  • This enzyme cleaves K48-linked ubiquitin chains in vitro.

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