INTRODUCTION Proteolysis Targeting Chimeras (PROTACs) represent a promising set of drugs that target proteins without an inherent enzymatic activity for proteasomal degradation. Despite all the efforts being invested in PROTAC...
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Ubiquitin and Neuroscience Neurodegenerative diseases are often characterized by excessive or dysfunctional proteins and protein aggregates, which induce specific pathological conditions. The ubiquitin proteasome system and autophagy play key roles…
LifeSensors is a proud sponsor of the EMBO Ubiquitin Workshop in Cavtat, Croatia from September 13-17, 2019! This workshop is important to the Ubiquitin community to inspire further progress and collaboration.
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LIFESENSORS ATTENDS BIO CONVENTION 2019 IN PHILADELPHIA The Bio International Convention will be in Philadelphia from June 3-6, 2019. More than 16,000 biotech and pharmaceutical leaders will attend and network to explore...
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Lewy Body Dementia (LBD) is a debilitating neurodegenerative disease that is increasingly becoming a public health concern. “In Lewy body dementia, alpha-synuclein forms into clumps inside neurons, starting in areas…
The Cold Spring Harbor Laboratory will be hosting a conference on the Ubiquitin Proteasome System (UPS) and associated Diseases April 23rd-27th. LifeSensors will be presenting on our most recent developments…
LifeSensors has spent years supporting the drug discovery efforts in Ubiquitin Proteasome System (UPS) research. We are excited to see this growing area of research gain more attention through conferences…
ABSTRACT Ubiquitin-Proteasome system (UPS), along with chaperone mediated-autophagy (CMA) and macroautophagy, constitutes the protein quality control system of the cell. The failure of these systems is particularly difficult to...
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SEE THE LIFESENSORS PRESENTATION ON NOVEL PROTAC ASSAYS HERE. PLEASE CONTACT US FOR MORE INFORMATION ON THIS EXCITING TECHNOLOGY- BD@LIFESENSORS.COM
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