UB219T: UBE2T, His6-SUMO

UBE2T can mediate the transfer of ubiquitin from ubiquitin-activating enzyme E1 to a substrate protein or E3 ligase. This E2 enzyme has been shown to be essential for the Fanconi anemia pathway. UBE2T conjugating activity is involved with the monoubiquitylation of FANCD2, co-functioning with the E3 ligase FANCL.

Info

Species	Human
Source	E. coli
Tag	His6-SUMO
Molecular Weight	34,540.3 Da
Quantity	0.8 nmol, 3.0 nmol
Concentration	40 µM
Formulation	25 mM Tris pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage	-80°C, avoid freeze/thaw cycles