October 22, 2024
October 22, 2024
TUBE LuxSit Fusion to Discover TPD Drugs
March 8, 2023
Drug Discovery with UbiTest Technology
UbiTest: Detection of polyubiquitinated proteins using TUBE based screening platforms by Gauthami S. Jalagadugula The…
December 14, 2022
Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation
Hijacking the natural mechanism of the Ubiquitin Proteasome System (UPS) is emerging as a powerful…
December 1, 2022
Discovering Unique Ubiquitin E3 Ligase Ligands to Unlock Targeted Protein Degradation
Discovering Unique Ubiquitin E3 Ligase Ligands to Unlock Targeted Protein degradation Gauthami Jalagadugula, Alexandra Russell1+,…
December 1, 2022
PROTACs and Molecular Glues: High-Throughput Quantitative Assays for Rationale Design
PROTACs and Molecular Glues: High-Throughput Quantitative Assays for Rationale Design Authors: Janelle Pedroza1, Kenneth Wallace1,…
November 4, 2019
Novel Approaches to PROTAC® Drug Discovery
INTRODUCTION Proteolysis Targeting Chimeras (PROTACs) represent a promising set of drugs that target proteins without…
November 6, 2018
PROTAC Method of Action Presentation
SEE THE LIFESENSORS PRESENTATION ON NOVEL PROTAC ASSAYS HERE. PLEASE CONTACT US FOR MORE INFORMATION ON…
July 10, 2018
New Developments in Ubiquitomics: Discovery of poly-ubiquitylated proteins by novel chain-selective TUBEs
LifeSensors Scientists Apurva Chaturvedi, Peter Foote, Li Liang, Dominic Vasturia, and Rajesh Singh recently presented…
April 19, 2018
Establishing Ubiquitylation Patterns in Cells: Efficient Monitoring of Oncogenic Ubiquitylation Activity
Lifesensors recently presented the work of Peter Foote, Xialong Lu, Apurva Chaturvedi, and Rajesh Singh…