By: Derrick Padykula and Isabelle Wentzel Hallmark of Neurodegeneration Diving into the complex world of neurodegeneration unveils the long road marked by the gradual decline of neuronal cells, ultimately leading to cell death. In Parkinson’s disease (PD) and Alzheimer’s disease (AD), the accumulation of aggregated proteins and dysfunctional mitochondria is what contributes to the demise of […]
[Malvern, PA, October 18, 2023] — LifeSensors Inc., a biotech company targeting the ubiquitin proteasome system for drug discovery and diagnostic markers, has received funding from the National Institute on Aging and National Institute of General Medicine. The funding, to the tune of $5.53 million, provides for the development of PROTAC drug discovery technologies. PROTACs […]
Current Paradigms and Innovative Research Dear Colleagues, Alzheimer’s and Parkinson’s diseases are the silent killers. Despite a massive investment, the failure rate in drug development is 99.6%. The largest hurdle in developing a radical therapy for Alzheimer’s disease (AD) and Parkinson’s Disease (PD) is a lack of a simple diagnostic blood test. Current diagnostics are […]
UBIQUITIN: HOPE FOR THE FUTURE OF ALZHEIMER’S RESEARCH by: Mark Tingey and Peter Foote Uncle Walt stared at us, not recognizing us or remembering our names. His eyes, which were once bright and filled with curiosity, were now fearful and withdrawn. He appeared to crumple in upon himself, as if the world he no longer […]
