SI3304: K33-Linked Tetra-Ubiquitin

Specifications

K33-linked ubiquitination is traditionally associated with regulation of the innate immune response. These chain types are also involved in protein stabilization and other non-degradative processes. K33 Tetra-Ubiquitin is a tetrameric chain of wild-type ubiquitin, wherein ubiquitin monomers are enzymatically linked together via an isopeptide bond between Lysine 33 and the C-terminal Glycine.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 34678 Da
Quantity Variable
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl
Storage -80°C, avoid freeze/thaw cycles

Additional information

SKU

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• Investigation of phosphoubiquitin chain specificity and selectivity
• Studies on the role of phosphoubiquitin chains in protein degradation pathways (e.g., proteasomal and autophagic degradation)
• Analysis of phosphoubiquitin-mediated signaling pathways and cellular responses
• Structural studies to elucidate the architecture and dynamics of phosphoubiquitin chains
• Screening assays to identify modulators of phosphoubiquitin chain assembly and disassembly processes