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SI218: Ubiquitin-K63R

LifeSensors SI218 is a 1 mg Ubiquitin-K63R protein used in biochemical research for studying ubiquitin signaling and protein regulation pathways. High purity, reliable quality.

$184.00

In stock

Applications

  • Investigation of E1-E2-E3 mediated ubiquitin ligation.
  • Investigation of DUB linkage specificity.
Recombinant ubiquitin having a single substitution of arginine for lysine at position 63. Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 8,592 Da
Quantity 1 mg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Applications

  • Investigation of E1-E2-E3 mediated ubiquitin ligation.
  • Investigation of DUB linkage specificity.

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