Specifications
LS E3 1017 is a derivative of thalidomide (Cat.No. PC-1006) and is commonly used as a precursor to PROTACs that hijack cereblon as the E3 ubiquitin ligase component. It is supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand.
Info
Purity | >98% |
Quantity | 5 mg, 10 mg, 25 mg |
Molecular Weight | 332.26 g/mol |
Physical State | Lyophilized off white solid |
Solubility | 30 mg/mL in DMSO |
CAS No. | 1061605-21-7 |
Storage | Room Temperature |
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