USP10 (Ubiquitin Specific Protease 10, UBPO) is a deubiquitinase that can remove conjugated ubiquitin from target proteins such as p53/TP53, BECN1, SNX3 and CFTR. In response to DNA damage, USP10 is translocated to the nucleus where it is involved in the deubiquitination of p53.
|Tag||His6 + SUMO|
|Molecular Weight||99 kDa|
|Formulation||25 mM Tris pH 7.5, 150 mM NaCl, 5 mM DTT, 10% glycerol|
|Storage||-80°C, avoid freeze/thaw cycles|