Cezanne (OTUD7B) is a deubiquitinase that preferentially cleaves K11 ubiquitin linkages. This enzyme was also shown to cleave K48- and K63-linked ubiquitin chains in vitro. It is known to be a negative regulator of NF-kB signaling.
|Tag||His6 + SUMO|
|Molecular Weight||103 kDa|
|Formulation||50 mM Tris-HCl pH 7.5, 150 mM NaCl, 5 mM DTT, 10% glycerol|
|Storage||-80°C, avoid freeze/thaw cycles|