UCH-L3 is a deubiquitinase that controls levels of cellular ubiquitin through the processing of ubiquitin precursors and ubiquitinated proteins. It is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. The activity of UCH-L3 is more than 200-fold higher than that of UCH-L1 when a fluorogenic for of ubiquitin is used as a substrate.
|Molecular Weight||25 kDa|
|Storage||-80°C, avoid freeze/thaw cycles|