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LifeSensors

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SI0602-5µg (panel) K6-linked (Ub2) di-ubiquitin

$65.00
  • Product Code: SI0602-5µg (panel) K6-linked (Ub2) diubiquitin
  • Availability: In Stock

K6-linked di-ubiquitin (Ub2) is a diubiquitin linked by a native isopeptide bond between the C-terminal glycine of the distal ubiquitin and the epsilon amino group of lysine 6 on the proximal ubiquitin. The product is generated using chemical ligation. It is a useful substrate for identifying and characterizing deubiquitinating enzymes that cleave the K6-linkage and for structural and binding studies of ubiquitin chain recognition by ubiquitin-associated domains (UBA) or ubiquitin-interacting motifs (UIMs).
Info

Purity

  > 95% by HPLC

Form

  Liquid

Molecular weight

  17,112 Da

Buffer

  10-20 mM Tris, pH 7.5, 0.15 M NaCl, 1 mM EDTA

Storage

  -80°C. Avoid repeated freeze/thaw cycles

Stability

  1 year under recommended storage conditions



Applications
  • Investigation of DUB linkage specificity.


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