Specifications
UBE2F is an E2 conjugation enzyme that is involved in the ubiquitylation of target substrates, along with E1 and E3 enzymes. UBE2F mediates the transfer of NEDD8 from NEDD8-activating enzyme E1 (UBA3-NAE1 complex) to a substrate protein. This E2 enzyme has been shown to associate with the both NEDD8 E3 ligase and RBX2, yet displays different target cullin specificities than a similar UBE2M/RBX1 E2/E3 complex.
Info
Species | Human |
Source | E. coli |
Tag | None |
Molecular Weight | 21,077.4 Da |
Quantity | 0.8 nmol, 3.0 nmol |
Concentration | Variable |
Formulation | 20 mM Tris pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol |
Storage | -80°C, avoid freeze/thaw cycles |
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