UB306: MuRF3

LifeSensors UB306 is a recombinant MuRF3 E3 ubiquitin ligase involved in ubiquitin conjugation to target proteins, essential for studying protein degradation and regulation.

$545.00

SKU UB-0306-0025 Categories E3 Ubiquitin Ligases, Ubiquitin Ligases and Enzymes Tag E3 ligase

In stock

Product Advantages

Applications

In vitro conjugation assay

MuRF3 is a RING domain E3 ligase that is involved in the conjugation of ubiquitin to target substrates. MuRF3 has been demonstrated to function with the E2 enzyme UBE2D3 (UbcH5c) in vitro. MuRF3 is also known as TRIM54 (tripartite motif-containing 54) containing a RING-finger/B-box/coiled-coil tripartite fold. MuRF3 has been implicated along with MuRF1 as a regulator of protein degradation in striated muscle. MuRF3 also plays an important role in maintaining cardiac function after myocardial infarction.

Info

Species	Human
Source	E. coli
Tag	His₆-SUMO
Molecular Weight	52.4 kDa (with tag), 40.3 (without tag)
Quantity	25 μg
Concentration	Variable
Formulation
Storage	-80°C, avoid freeze/thaw cycles