UB225: UBE2Q2

SKU UB-0225 Categories E2 Ubiquitin Conjugating Enzymes, Ubiquitin Ligases and Enzymes

LifeSensors UB225 (UBE2Q2) is a ubiquitin-conjugating E2 enzyme involved in protein ubiquitination, key for studying protein degradation and cellular regulation.

Price range: $196.00 through $390.00

UBE2Q2, a member of the Ubc2 family of ubiquitin-conjugating E2 enzymes, was originally discovered as a differentially expressed gene in the endometrium of rabbits. Further studies have shown that the enzyme is involved in cell cycle regulation and inhibition of its activity leads to mitotic arrest in the presence of microtubule inhibiting agents. UBE2Q2 message and protein levels are elevated in human head and neck squamous cell carcinomas. UBE2Q2 is homologous to the UBC2 family of enzymes, and isoforms are present in a broad range of species.

Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	42,818.4 Da
Quantity	0.8 nmol, 3.0 nmol
Concentration	40 µM
Formulation	TBS, 10% glycerol
Storage	-80°C, avoid freeze/thaw cycles

Datasheet

Identify cognate E2/E3 pairs
Characterize upregulation/downregulation of E2 enzymes
Build poly-ubiquitin chains
Characterize ubiquitin chain specificity of E2 enzymes
Analyze expression of E2 enzymes

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All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

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All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

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All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

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UB225: UBE2Q2

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