Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UB222: UBE2C (Ubc10)

LifeSensors UB222 (UBE2C/Ubc10) is an E2 ubiquitin conjugating enzyme essential for protein ubiquitylation, playing a key role in targeted protein degradation pathways.

Price range: $196.00 through $390.00

UBE2C (also known as Ubc10) is an E2 conjugation enzyme that is involved in the ubiquitylation of target substrates, along with E1 and E3 enzymes. UBE2C interacts with the Anaphase Promoting Complex (APC) and, as a member of this complex, functions to ubiquitylate substrates and target these substrates, which include several cyclins, for degradation. As such, UBE2C plays a critical role in cell cycle progression and has recently been shown to play a key role in tumorigenesis.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 19,652.6 Da
Quantity 0.8 nmol, 3.0 nmol
Concentration 40 µM
Formulation 25 mM Tris pH 7.4, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Applications

  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes

Benefits

  • Untagged (native) E2 conjugation enzyme

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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