UB209: UBE2R2 (Ubc3B)

LifeSensors UB209: UBE2R2 (Ubc3B) is an E2 ubiquitin-conjugating enzyme, similar to UBC3/CDC34. It participates in the ubiquitylation pathway, with applications in protein regulation research

Price range: $245.00 through $439.00

SKU UB-0209 Categories E2 Ubiquitin Conjugating Enzymes, Ubiquitin Ligases and Enzymes

Product Advantages

Identify cognate E2/E3 pairs
Characterize upregulation/downregulation of E2 enzymes
Build poly-ubiquitin chains
Characterize ubiquitin chain specificity of E2 enzymes
Analyze expression of E2 enzymes

Benefits

Untagged (native) E2 conjugation enzyme

UBE2R2 is similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. UBE2R2 is a 238 amino acid (27.2 kD) pre-protein from chromosome 9. After CK2-mediated UBE2R2 phoshorylation, it binds to the F-Box protein beta-TrCP, which is the subunit recognition subunit of an SCF E3 ligase. UBE2R2 may be involved in degradation of beta-catenin.

Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	27,166.1 Da
Quantity	0.8 nmol, 3.0 nmol
Concentration	40 µM
Formulation	TBS
Storage	-80°C, avoid freeze/thaw cycles