Questions about a product, technology or experimental design? Give us a call 610-644-8845. For special institutional pricing, check out our Distributors!
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

SP4010: SUMO Protease 1

LifeSensors SP4010 is a highly active recombinant SUMO Protease 1 (Ulp1) that specifically cleaves SUMO tags from fusion proteins, enabling precise protein purification and functional assays.

Price range: $382.00 through $5,192.00

For removal of SUMO (smt3) tags from fusion proteins expressed using SUMOpro systems (Cat#s: 1000A, 1000K, 1001A, 1001K). LifeSensors’ industry leading SUMO Protease 1 (Ulp1), a highly active and robust recombinant protease, cleaves SUMO from recombinant fusion proteins. Unlike thrombin, EK, or TEV protease, which recognize short linear sequences, SUMO Protease 1 recognizes the tertiary structure of SUMO. As a result, SUMO Protease 1 will not cleave within the fused protein of interest. By purchasing this product, the purchaser agrees to comply with the terms of our Limited Use Label License. Need bulk quantities? We would be happy to work out a custom price that fits your budget. Please click here to request a quote.

Info

Species Human
Source E. coli
Tag His6 
Molecular Weight 26,595.4 Da
Quantity 250, 500, 1000, 5000 units
Concentration Variable
Formulation 50 mM Hepes pH 7.5, 150 mM NaCl, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Applications

  • Digestion and removal of SUMOpro tags from recombinant fusion proteins made with our SUMOpro Expression systems (Cat#s: 1000A, 1000K, 1001A, 1001K)

Benefits

  • SUMO Protease 1 cleaves consistently over a broad range of temperature (30°C is optimal), pH [5.5 – 9.5], and ionic strength. SUMO Protease 1 contains a polyhistidine tag at the N-terminus, making it easy to remove from the cleavage reaction by affinity chromatography.

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
We typically respond within 24 hours

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271 Great Valley Parkway Malvern, PA 19355

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PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

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